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Clinical Need
Lung cancer is the leading cause of cancer death for both men and women. More people die of lung cancer than of colon, breast and prostate cancers combined. According to the World Health Organization, lung cancer (both non-small cell and small cell type) affects more than 1.2 million patients a year, with around 1.1 million deaths annually and around 500,000 in the U.S., Europe and Japan. About 85 percent of all lung cancers are the non-small cell type. Further, only about 15 percent of people diagnosed with NSCLC survive this disease after five years. For most patients with NSCLC, current treatments provide limited success.
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